How to culturally adapt healthcare interventions

Cultural adaptations of healthcare interventions are widely advocated to improve effectiveness, acceptability, and equity for diverse populations. Despite the existence of several cultural adaptation frameworks, there remains a lack of practical, transferable guidance on how adaptations are undertaken in applied healthcare settings. Adaptation processes are frequently underreported, limiting transparency, reproducibility, and learning across studies, especially within a UK context.

We have produced a step-by-step guide which provides practical direction on how to plan, implement, document, and refine cultural adaptations across a healthcare intervention.

Key reflections from the guide are that cultural adaptations should be considered as cyclical processes rather than linear; deep-level adaptations often require reframing intervention assumptions; and sustained stakeholder collaboration is essential for maintaining intervention fidelity while improving cultural relevance. The guide is designed to be transferable across populations, settings, and intervention types.

You can download the guide and roadmap here:

Step by step guide for culturally adapting healthcare interventions

Guide to culturally adapting interventions

Interactive roadmap for cultural adaption  for healthcare equity

Interactive roadmap for cultural adaptation

Developed by Ed Breckin, 2026